Reactions to Total Dose Infusion of Iron Dextran in Rheumatoid Arthritis

Total-dose infusion of iron-dextran in rheumatoid arthritis.

Ten patients with active rheumatoid arthritis were given a total dose infusion of iron dextran for anaemia. One had an immediate anaphylactoid reaction; the other nine had a brief exacerbation of arthralgia and joint dysfunction of up to seven days' duration. The erythrocyte sedimentation rate rose by an average of 23 mm. in one hour (Westergren), but this often took longer than seven days to s...

Reactions to Total Dose Intravenous Infusion of Iron Dextran (imferon).

Increased transfer of iron to the fetus after total dose infusion of iron dextran during pregnancy.

After total dose infusion of iron dextran to 14 pregnant women the saturation of transferrin and the concentration of ferritin were increased in the cord blood at birth, compared with untreated cases. These changes suggest that the fetal iron stores may be increased by such treatment.

Total dose imferon (iron-dextran complex) infusion therapy in severe hookworm anaemia.

Skin inflammatory reactions to capsaicin in rheumatoid arthritis patients compared to healthy controls

Objective: Previous studies have examined the role of sensory nerves and neural mediators in symmetrical joint inflammation and autoimmunity in rheumatoid arthritis (RA). In this study, we sought to examine the association between capsaicin skin test and disease activity in RA patients. Materials and Methods: Eighty RA patients (case group) and 20 healthy volunteers were enrolled in this experi...